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Marijuana is normally considered the least harmful of the prohibited drugs, and certainly, the short-term negative results of marijuana use are not as discernible as with other illegal substances. But even if the damage done is comparatively minor, when we consider the vast numbers of marijuana users, marijuana may in point of fact be doing more damage than any other drug on the market! Lots of persons believe that marijuana is not a dangerous drug and that it should be as legal to buy and use as liquor. Marijuana is the most commonly used illegal drug in the industrialised world and, besides alcohol, marijuana is the most commonly used drug by young folks. Marijuana is a dry, shredded olive/brown mix of buds, sticks, seeds, and leaves of the hemp plant, Cannabis sativa. It is normally smoked as a cigarette (joint, reefer), or in a pipe (bong). It also is smoked in blunts, which are cigars that have been emptied of tobacco and refilled with marijuana, often in combination with a further drug. It may also be blended in food or concocted as a tea. As a more concentrated, gummy form it is named hashish and, as a tacky dark liquid, hash oil. Marijuana use has a strong and distinct, commonly sweet-and-sour odor. Some folks believe that the smoke smells like burning rope. There are a number of street terms for marijuana including pot, herb, weed, grass, widow, ganja, and hash, as well as terms derived from trademarked kinds of cannabis, such as Bubble Gum, Northern Lights, Fruity Juice, Afghani #1, and a number of Skunk varieties. The main functional chemical in marijuana is THC (delta-9-tetrahydrocannabinol). The membranes of certain nerve cells in the brain contain protein receptors that bind to THC. Once securely positioned, THC launches a series of molecular reactions that ultimately lead to the high that smokers experience when they use marijuana. Scientists have learned a great deal about how THC acts in the brain to produce its many consequences. When someone uses marijuana, THC rapidly passes from the lungs into the bloodstream, which transports the chemical to different organs throughout the body, including the brain. In the brain, THC attaches to certain regions known as 'cannabinoid receptors' on nerve cells and affects the activity of those cells. Some brain areas have many cannabinoid receptors; some others have few or none. Many cannabinoid receptors are found in the parts of the brain that effect pleasure, memory recall, thinking, concentration, sensory and time awareness, and coordinated movement. The short-term results of marijuana can incorporate difficulties with memory and learning, distorted perception, difficulty in thinking and problem-solving, loss of coordination and increased heart rate. Research findings for long-term marijuana misuse indicate some variations in the brain similar to those seen after long-term abuse of other major drugs. Marijuana can also have an unfavourable effect on the heart. One research experiment has discovered that an abuser's risk of heart disease more than quadruples in the initial hour after smoking marijuana. The scientists propose that such an influence might result from marijuana's effects on blood pressure and pulse rate and reduced oxygen-carrying capacity of blood. A user's lungs are also affected. A study of 450 individuals found that persons who smoke marijuana frequently but do not use tobacco have more health problems and miss more days of work than nonsmokers. Many of the additional sick days among the marijuana smokers in the study were for respiratory illnesses. Even infrequent use can end up causing burning and pain of the mouth and throat, often accompanied by a heavy cough. Someone who smokes marijuana regularly may have many of the same breathing complications that tobacco users do, such as daily cough and phlegm development, more regular acute chest illness, a heightened risk of lung infections, and a bigger tendency to obstructed airways. Smoking marijuana possibly increases the likelihood of developing cancer of the head or neck. A research experiment comparing 173 cancer sufferers and 176 healthy people produced evidence that marijuana smoking doubled or tripled the risk of these malignant tumors. Marijuana abuse also has the potential to promote cancer of the lungs and other regions of the respiratory tract because it contains irritants and cancer causing chemicals. In fact, marijuana smoke is comprised of 50 to 70 percent more cancer-causing hydrocarbons than does tobacco smoke. It also induces high levels of an enzyme that converts certain hydrocarbons into their carcinogenic form -levels that may accelerate the variations that ultimately produce malignant cells. Marijuana smokers commonly inhale more deeply and hold their breath longer than tobacco smokers do, which elevates the lungs' exposure to carcinogenic smoke. These facts propose that, puff for puff, smoking marijuana may be more dangerous to the lungs than inhaling tobacco. Some of marijuana's adverse health consequences may occur because THC impairs the immune system's capability to fight illness. In laboratory experiments that exposed animal and humanoid cells to THC or other marijuana ingredients, the normal disease-preventing reactions of many of the key types of immune cells were inhibited. In other experiments, mice exposed to THC or related substances were more prone than unexposed mice to contract bacterial infections and tumors. Research clearly indicates that marijuana has the potential to cause difficulties in everyday life or make a person's current complications more serious. Depression, anxiety, and personality disturbances have been linked with persistent marijuana use. Because marijuana compromises the capacity to learn and remember information, the more a person uses marijuana the more he or she is liable to fall behind in accumulating educational, job, or social skills. Moreover, study has found that marijuana's adverse influence on memory and learning can last for days or weeks after the acute results of the drug wear off. Students who smoke marijuana get poorer grades and are less likely to graduate from high school, compared with their nonsmoking peers. A research experiment of 129 university students discovered that, among those who smoked the drug at least 27 of the 30 days subsequent to being surveyed, crucial skills related to attention, memory recall, and learning were appreciably diminished, even after the students had not taken the drug for at least 24 hours. These "serious" marijuana users had more trouble sustaining and shifting their concentration and in chronicling, organizing, and using data than did the study participants who had used marijuana no more than 3 of the previous 30 days. As a result, a person who uses marijuana each day may be operating at a reduced educational capacity all of the time. More recently, the same researchers discovered that the capacity of a group of long-term serious marijuana smokers to recall words from a list remained diminished for a week after abstaining, but returned to normal within four weeks. Thus, some intellectual abilities may be restored in people who quit inhaling marijuana, even after long-term heavy use. Workers who use marijuana are more liable than their peers to have problems on the job. Several studies connect workers' marijuana inhaling with increased absences, tardiness, accidents, workers' compensation claims, and job turnover. A study among post-office workers discovered that employees who tested positive for marijuana on a pre-employment urine drug test had 55 percent more industrial mishaps, 85 percent more injuries, and a 75-percent increase in nonattendance compared with those who tested negative for marijuana use. In an additional research experiment, heavy marijuana abusers said that the drug diminished many important measures of life achievement including cognitive abilities, career standing, social life, and physical and mental health. Research has shown that some newborns born to women who smoked marijuana during their gestation exhibit altered responses to pictorial stimulation, increased tremulousness, and a high-pitched cry, which may indicate neurological difficulties in development. During the preschool period, marijuana-exposed children have been observed to perform tasks involving unbroken attention and memory more poorly than non-exposed children do. In the school years, these children are more likely to display deficits in problem-solving skills, memory recall, and the capability to remain focused. Long-term marijuana abuse can lead to addiction for some people. That is, they misuse the drug compulsively even though it interferes with family, school, work, and recreational activities. Drug craving and withdrawal indicators can make it hard for long-term marijuana users to stop abusing the drug. People striving to quit describe touchiness, insomnia, and anxiety. They also exhibit increased anger on psychological tests, peaking about one week after the last use of the drug.
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